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      <image:title>News (old) - SNIPR Biome announces opening of new BSL2/GMO2-classified laboratory in Copenhagen, Denmark - Make it stand out</image:title>
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      <image:title>The Gut Microbiome - The Gut Microbiome</image:title>
      <image:caption>Trillions of healthy bacteria live inside the human gut. It is estimated that the number of microbes reach 10^12 per gram in the human large intestine (luminal content of the colon) where these bacteria play a crucial role both in physiology and health as well as influence the cause of disease. The gut microbiome performs a number of crucial functions for the host from helping to digest our food, to produce vitamins and priming our immune system to tolerance - thus, these vast numbers of bacteria live in a complex symbioses with their host. In healthy individuals the human microbiome is dominated by two large Phyla: Bacteroidetes and Firmicutes with smaller representations from Proteobacteria and Actinobacteria. In some cases the body reacts badly to its own bacteria, which can lead to immune stimulation and gut inflammation. There is an increasing understanding that perturbations and large changes in the microbiome (dysbiosis) are associated with human disease and that specifically addressing the human gut microbiome composition can represent an attractive medical and pharmacological avenue. We aim to be able to make targeted microbiome engineering with our CRISPR-based precision medicines.</image:caption>
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      <image:title>The Gut Microbiome - The Gut Microbiome</image:title>
      <image:caption>Trillions of healthy bacteria live inside the human gut. It is estimated that the number of microbes reach 10^12 per gram in the human large intestine (luminal content of the colon) where these bacteria play a crucial role both in physiology and health as well as influence the cause of disease. The gut microbiome performs a number of crucial functions for the host from helping to digest our food, to produce vitamins and priming our immune system to tolerance - thus, these vast numbers of bacteria live in a complex symbioses with their host. In healthy individuals the human microbiome is dominated by two large Phyla: Bacteroidetes and Firmicutes with smaller representations from Proteobacteria and Actinobacteria. In some cases the body reacts badly to its own bacteria, which can lead to immune stimulation and gut inflammation. There is an increasing understanding that perturbations and large changes in the microbiome (dysbiosis) are associated with human disease and that specifically addressing the human gut microbiome composition can represent an attractive medical and pharmacological avenue. We aim to be able to make targeted microbiome engineering with our CRISPR-based precision medicines.</image:caption>
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      <image:title>Approach - The Gut Microbiome</image:title>
      <image:caption>Trillions of healthy bacteria live inside the human gut. It is estimated that the number of microbes reach 10^12 per gram in the human large intestine (luminal content of the colon) where these bacteria play a crucial role both in physiology and health as well as influence the cause of disease. The gut microbiome performs a number of crucial functions for the host from helping to digest our food, to produce vitamins and priming our immune system to tolerance - thus, these vast numbers of bacteria live in a complex symbioses with their host. In healthy individuals the human microbiome is dominated by two large Phyla: Bacteroidetes and Firmicutes with smaller representations from Proteobacteria and Actinobacteria. In some cases the body reacts badly to its own bacteria, which can lead to immune stimulation and gut inflammation. There is an increasing understanding that perturbations and large changes in the microbiome (dysbiosis) are associated with human disease and that specifically addressing the human gut microbiome composition can represent an attractive medical and pharmacological avenue. We aim to be able to make targeted microbiome engineering with our CRISPR-based precision medicines.</image:caption>
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      <image:title>Approach - SNIPR is making CRISPR-based precision medicines to target the world’s superbugs</image:title>
      <image:caption>A silent pandemic of antimicrobial resistant (AMR) bacterial pathogens is on the rise and we risk living in a future where antibiotics are no longer effective. SNIPR is making precision medicines to target these harmful bacteria. The majority of bacteria living within your body are good, so we only want to remove the harmful ones. Our CRISPR technology is designed to function exclusively in bacteria and by programming our proprietary CRISPR platform, we can very precisely find and cut specific DNA in the target bacteria of our choice to kill those and leaving the good bacteria untouched. We deliver our CRISPR precision cargo by two complementary delivery vehicles, either phages, which are viruses that only kill bacteria or via good bacteria that we engineer to transfer our CRISPR-cargo to the target bacteria. We are world-leading in CRISPR-arming and engineering both phages and the good bacteria to become efficient bacterial killers. Read about our technology Our CRISPR and delivery platforms have been validated by our strong collaborations and are agnostic to any antibiotic resistance carried by the bacteria. The platforms are therefore well suited to tackle the global AMR crisis. We are currently applying our platform technology to target critical pathogens and antimicrobial resistances that are also at the top of recent pathogen priority lists by WHO and CDC. See our pipeline</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/68d106887056c731a8673361/1758529218119-K31JXVD5KWTG9SBC5ZE3/Patient_Focus_Vertical.jpg</image:loc>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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