Using SNIPR Biome’s proprietary adaptation of natural CRISPR systems, engineering can be precisely targeted to the desired bacterial species or strain whilst minimizing development of resistance to treatment. Our technology harnesses bacterial endogenous Cas nuclease activity, fatally turning the cells’ own machinery on itself. Using carefully designed CRISPR-Guided Vectors™, very selective manipulations can shape complex microbial communities, including the human gut microbiome.